The Isolation of 6a-Hydroxyoestrone from the Urine of Pregnant Women


1. In view of previous experiments in vitro and in vivo, in which 6-hydroxylation of phenolic steroids by various tissues was demonstrated, an attempt was made to isolate 6-hydroxy oestrogens from the urine of pregnant women. 2. During this work it was found that free 6cas well as 6fl-hydroxylated oestrogens were extremely unstable under acidic conditions… (More)


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