The Iowa 500: suicide in mania , depression, and schizophrenia.

@article{Winokur1975TheI5,
  title={The Iowa 500: suicide in mania , depression, and schizophrenia.},
  author={George Winokur and Ming T. Tsuang},
  journal={The American journal of psychiatry},
  year={1975},
  volume={132 6},
  pages={650-1}
}
Long-term (30-to 40-year) follow-up data for 76 manic patients, 182 depressives. 170 schizophrenics, and 109 controls showed that 10 per cent of the schizophrenics, 8.5 percent of the manics, and 10.6 percent of the depressives who were decreased had died by suicide. None of the controls had committed suicide. The authors suggest that suicide is a significant outcome factor in all three of these illnesses and is likely to occur at an earlier age in schizophrenia than in the other illnesses. 

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