The Intra- or Extracellular Redox State Was Not Affected by a High vs. Low Glycemic Response Diet in Mice

@inproceedings{Kleckner2015TheIO,
  title={The Intra- or Extracellular Redox State Was Not Affected by a High vs. Low Glycemic Response Diet in Mice},
  author={Amber S. Kleckner and Siu Fun Wong and Barbara E Corkey and Ra{\'u}l M Luque},
  booktitle={PloS one},
  year={2015}
}
A low glycemic response (LGR) vs. high glycemic response (HGR) diet helps curtail the development of obesity and diabetes, though the mechanisms are unknown. We hypothesized that consumption of a HGR vs. a LGR diet would lead to a more oxidized circulating redox state and predicted that a HGR diet would increase fat accumulation, reduce insulin sensitivity, and impair metabolic acclimation to a high fat diet in a mouse model. Hence, male C57BL/6 mice consumed a HGR or LGR diet for 16 weeks and… CONTINUE READING

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