The Intertwining of Transposable Elements and Non-Coding RNAs

@inproceedings{Hadjiargyrou2013TheIO,
  title={The Intertwining of Transposable Elements and Non-Coding RNAs},
  author={Michael Hadjiargyrou and Nicholas Delihas},
  booktitle={International journal of molecular sciences},
  year={2013}
}
Growing evidence shows a close association of transposable elements (TE) with non-coding RNAs (ncRNA), and a significant number of small ncRNAs originate from TEs. Further, ncRNAs linked with TE sequences participate in a wide-range of regulatory functions. Alu elements in particular are critical players in gene regulation and molecular pathways. Alu sequences embedded in both long non-coding RNAs (lncRNA) and mRNAs form the basis of targeted mRNA decay via short imperfect base-pairing… CONTINUE READING