The Interplay of Lipids, Lipoproteins, and Immunity in Atherosclerosis.

  title={The Interplay of Lipids, Lipoproteins, and Immunity in Atherosclerosis.},
  author={Angela Pirillo and Fabrizia Bonacina and Giuseppe D. Norata and Alberico L. Catapano},
  journal={Current atherosclerosis reports},
  volume={20 3},
PURPOSE OF REVIEW Atherosclerosis is an inflammatory disorder of the arterial wall, in which several players contribute to the onset and progression of the disease. Besides the well-established role of lipids, specifically cholesterol, and immune cell activation, new insights on the molecular mechanisms underlying the atherogenic process have emerged. RECENT FINDINGS Meta-inflammation, a condition of low-grade immune response caused by metabolic dysregulation, immunological memory of innate… CONTINUE READING
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