The Interplay between PP2A and microRNAs in Leukemia

@inproceedings{Ruvolo2015TheIB,
  title={The Interplay between PP2A and microRNAs in Leukemia},
  author={Peter P Ruvolo},
  booktitle={Front. Oncol.},
  year={2015}
}
Protein phosphatase 2A (PP2A) is a serine/threonine phosphatase family whose members have been implicated in tumor suppression in many cancer models. In many cancers, loss of PP2A activity has been associated with tumorigenesis and drug resistance. Loss of PP2A results in failure to turn off survival signaling cascades that drive drug resistance such as… CONTINUE READING