The Interaction Between Intrathecal Administration of Low Doses of Palmitoylethanolamide and AM251 in Formalin-Induced Pain Related Behavior and Spinal Cord IL1-β Expression in Rats

Abstract

Most of the modulating effects of cannabinoids on pain are through putative cannabinoid CB1 and CB2 receptors. However, the involvement of other receptors is also suggested. Cannabinoid compounds with analgesic activity such as palmitoylethanolamide (PEA) show low affinity to CB1 and CB2 receptors, yet selectively activate GPR55 receptors. The objective of… (More)
DOI: 10.1007/s11064-011-0672-2

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@article{Naderi2011TheIB, title={The Interaction Between Intrathecal Administration of Low Doses of Palmitoylethanolamide and AM251 in Formalin-Induced Pain Related Behavior and Spinal Cord IL1-β Expression in Rats}, author={Nima Mehdizadeh Naderi and Mohsen Majidi and Zahra Mousavi and Solaleh Khoramian Tusi and Zahra Mansouri and Fariba Khodagholi}, journal={Neurochemical Research}, year={2011}, volume={37}, pages={778-785} }