The Ins and Outs of the BCCAo Model for Chronic Hypoperfusion: A Multimodal and Longitudinal MRI Approach

@inproceedings{Soria2013TheIA,
  title={The Ins and Outs of the BCCAo Model for Chronic Hypoperfusion: A Multimodal and Longitudinal MRI Approach},
  author={Guadalupe Soria and Ra{\'u}l Tudela and Ana M{\'a}rquez-Mart{\'i}n and Llu{\"i}sa Cam{\'o}n and Dafnis Batalle and Emma Mu{\~n}oz-Moreno and Elisenda Eixarch and Josep Puig and Salvador Pedraza and Elisabet Vila and Alberto Prats-Galino and Anna M Planas},
  booktitle={PloS one},
  year={2013}
}
Cerebral hypoperfusion induced by bilateral common carotid artery occlusion (BCCAo) in rodents has been proposed as an experimental model of white matter damage and vascular dementia. However, the histopathological and behavioral alterations reported in this model are variable and a full characterization of the dynamic alterations is not available. Here we implemented a longitudinal multimodal magnetic resonance imaging (MRI) design, including time-of-flight angiography, high resolution T1… CONTINUE READING

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Mentioned Connections BETA
GliosisNo subtypeNecrosis
The patterns of MRI alterations were related to either ischemic necrosis or gliosis .
NecrosisNo subtypeGliosis
The patterns of MRI alterations were related to either ischemic necrosis or gliosis .
Here we implemented a longitudinal multimodal magnetic resonance imaging ( MRI ) design , including time - of - flight angiography , high resolution T1-weighted images , T2 relaxometry mapping , diffusion tensor imaging , and cerebral blood flow measurements up to 12 weeks after BCCAo or sham - operation in Wistar rats .
Here we implemented a longitudinal multimodal magnetic resonance imaging ( MRI ) design , including time - of - flight angiography , high resolution T1-weighted images , T2 relaxometry mapping , diffusion tensor imaging , and cerebral blood flow measurements up to 12 weeks after BCCAo or sham - operation in Wistar rats .
Here we implemented a longitudinal multimodal magnetic resonance imaging ( MRI ) design , including time - of - flight angiography , high resolution T1-weighted images , T2 relaxometry mapping , diffusion tensor imaging , and cerebral blood flow measurements up to 12 weeks after BCCAo or sham - operation in Wistar rats .
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