The Innate Immune Receptor PGRP-LC Controls Presynaptic Homeostatic Plasticity

@article{Harris2015TheII,
  title={The Innate Immune Receptor PGRP-LC Controls Presynaptic Homeostatic Plasticity},
  author={Nathan Harris and Daniel J. Braiser and Dion K Dickman and Richard Doty Fetter and Amy Tong and Graeme W Davis},
  journal={Neuron},
  year={2015},
  volume={88},
  pages={1157-1164}
}
It is now appreciated that the brain is immunologically active. Highly conserved innate immune signaling responds to pathogen invasion and injury and promotes structural refinement of neural circuitry. However, it remains generally unknown whether innate immune signaling has a function during the day-to-day regulation of neural function in the absence of… CONTINUE READING