The Influence of Innate and Adaptive Immunity on Crohn’s Disease Severity

Abstract

Stricturing and penetrating disease are classified as severe Crohn’s disease types and are frequently associated with an increased risk for bowel surgery. Research has shown that early treatment with aggressive immunosuppression (including biological and thiopurine therapies – the so-called “top-down approach”) results in a diminished risk of developing… (More)

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Cite this paper

@inproceedings{Azzopardi2014TheIO, title={The Influence of Innate and Adaptive Immunity on Crohn’s Disease Severity}, author={Neville Azzopardi and Keith A Sacco and Godfrey Grech}, year={2014} }