The Influence of Fine Excipient Particles on the Performance of Carrier-Based Dry Powder Inhalation Formulations

@article{Jones2006TheIO,
  title={The Influence of Fine Excipient Particles on the Performance of Carrier-Based Dry Powder Inhalation Formulations},
  author={Matthew D. Jones and Robert Price},
  journal={Pharmaceutical Research},
  year={2006},
  volume={23},
  pages={1665-1674}
}
The inclusion of a small amount of fine particle excipient in a carrier-based dry powder inhalation system is a well researched technique to improve formulation performance and is employed in the pharmaceutical industry. The removal of intrinsic fines from a lactose carrier has been found to decrease formulation performance, whereas adding fines of many different materials into formulations increased performance. Changing the particle size of these fines, the amount added and the technique by… CONTINUE READING

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