The Influence of Adrenocorticotropin on Transport of a Cholesteryl Linoleate-Low Density Lipoprotein Complex into Adrenal Tumor Cells *

Abstract

The action of adrenocorticotropin (ACTH) on the specific (receptor-mediated) uptake of cholesteryl linoleate *low density lipoprotein complexes was examined in Y-l mouse adrenal tumor cells. High affinity binding (I& 4.1 x 10” M) was observed with ACTH; lower affinity was seen in the absence of ACTH. The effect of ACTH was observed within 10 min at… (More)

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