The InflammTORy Powers of Senescence.

Abstract

Cellular senescence is accompanied by secretion of cytokines and ensuing inflammation. Recent work reveals that mTOR is crucial for the secretory phenotype of senescent cells. These findings open the possibility of disabling the pathological effects of senescence with mTOR inhibitors and may explain the anti-aging properties of rapamycin. 
DOI: 10.1016/j.tcb.2015.09.011

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