The Infection Hypothesis of Schizophrenia: A Systematic Review

  title={The Infection Hypothesis of Schizophrenia: A Systematic Review},
  author={A. Scharko},
  journal={Journal of Behavioral and Brain Science},
  • A. Scharko
  • Published 2011
  • Medicine
  • Journal of Behavioral and Brain Science
Objectives: The objective of this paper is to accomplish a systematic review of the infection hypothesis of schizophrenia. Methods: All English language publications from January 1989 to March 2010 as related to infection and schizophrenia were obtained. Each study selected for analysis must either deal with the direct infection of an individual and schizophrenia or maternal infection during pregnancy and the subsequent development of schizophrenia in the offspring. The primary outcome measure… Expand
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Serious viral CNS infections during childhood appear to be associated with the later development of schizophrenia and nonaffective psychoses, and the association with specific viruses suggests that the risk is related to infectious agents with a propensity to invade the brain parenchyma. Expand
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  • J. Mcgrath, D. Castle
  • Psychology, Medicine
  • The Australian and New Zealand journal of psychiatry
  • 1995
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