The Impact of Zonisamide on the Development and Course of Alcohol Dependence in Rabbits. A pharmaco-EEG study.

@article{KrupaBurtnik2017TheIO,
  title={The Impact of Zonisamide on the Development and Course of Alcohol Dependence in Rabbits. A pharmaco-EEG study.},
  author={Agata Krupa-Burtnik and Ewa Zwierzyńska and Anna Kordala and Boguslawa Pietrzak},
  journal={Alcohol and alcoholism},
  year={2017},
  volume={52 3},
  pages={
          282-288
        }
}
Aims Zonisamide is a new anti-epileptic drug whose mechanism of action is associated with neurotransmission systems also involved in the pathogenesis of addiction. Recently, the role of memory processes and the hippocampus (Hp) is underlined in dependence. In our previous study, we determined that zonisamide decreases changes in hippocampal bioelectric activity induced by a single dose of ethanol. Methods This study uses a pharmaco-EEG method to examine the impact of zonisamide on the… CONTINUE READING
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