The Impact of Interventions to Improve Sleep on Delirium in the ICU: A Systematic Review and Research Framework*

@article{Flannery2016TheIO,
  title={The Impact of Interventions to Improve Sleep on Delirium in the ICU: A Systematic Review and Research Framework*},
  author={Alexander H. Flannery and Douglas R. Oyler and Gerald L. Weinhouse},
  journal={Critical Care Medicine},
  year={2016},
  volume={44},
  pages={2231–2240}
}
Objective :This study aimed to assess whether interventions targeted at improving sleep in the ICU were associated with reductions in ICU delirium. Secondary outcomes include duration of delirium and ICU length of stay. Data Sources:MEDLINE, CINAHL, Web of Science, Scopus, WorldCat, and International Pharmaceutical Abstracts were searched from inception to January 2016. Study Selection:Studies investigating any type of sleep intervention (nonpharmacologic or pharmacologic) and assessing the… 
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Delirium Transitions in the Medical ICU: Exploring the Role of Sleep Quality and Other Factors*
TLDR
Infusion of benzodiazepine and/or opioid medications was strongly associated with transition to delirium in the ICU in mechanically ventilated patients and is an important, modifiable risk factor for deliria in critically ill patients.
The Effect of a Quality Improvement Intervention on Perceived Sleep Quality and Cognition in a Medical ICU*
TLDR
An ICU-wide quality improvement intervention to improve sleep anddelirium is feasible and associated with significant improvements in perceived nighttime noise, incidence of delirium/coma, and daily delirio-coma-free status.
A Pilot Study to Test the Feasibility of a Nonpharmacologic Intervention for the Prevention of Delirium in the Medical Intensive Care Unit
TLDR
A multicomponent prevention protocol consisting of sedation cessation, sleep-wake cycles, sensory stimulation, mobility, and music tested for prevention of delirium found little difference before and after intervention.
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Randomized ICU Trials Do Not Demonstrate an Association Between Interventions That Reduce Delirium Duration and Short-Term Mortality: A Systematic Review and Meta-Analysis*
TLDR
A review of current evidence fails to support that ICU interventions that reduce delirium duration reduce short-term mortality, and meta-regression revealed that delIRium duration was not associated with reduced short- term mortality.
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TLDR
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TLDR
Sleep deprivation may prove to be a modifiable risk factor for the development of delirium with important implications for the acute and long-term outcome of critically ill patients.
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TLDR
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Developing, Implementing, and Evaluating a Multifaceted Quality Improvement Intervention to Promote Sleep in an ICU
  • B. Kamdar, Jessica Yang, D. Needham
  • Medicine
    American journal of medical quality : the official journal of the American College of Medical Quality
  • 2014
TLDR
The present article describes the specific QI framework used to develop and implement this intervention, which consists of summarizing the evidence to create a list of sleep-promoting interventions and selecting performance measures to assess intervention adherence and patient outcomes.
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