The Impact of Genome Region of Difference 4 (RD4) on Mycobacterial Virulence and BCG Efficacy

@inproceedings{Ru2017TheIO,
  title={The Impact of Genome Region of Difference 4 (RD4) on Mycobacterial Virulence and BCG Efficacy},
  author={Huanwei Ru and Xiaojia Liu and Chen Luh Lin and Jingyan Yang and Fuzeng Chen and Ruifeng Sun and Lu Zhang and Jun Liu},
  booktitle={Front. Cell. Infect. Microbiol.},
  year={2017}
}
Comparative genome analyses have revealed a number of regions of difference (RD) among mycobacterial species. The functional consequences of most of these genome variations have not been studied. RD4, which encompasses Rv1506c-Rv1516c of Mycobacterium tuberculosis (M. tb) H37Rv, is absent in the closely related Mycobacterium bovis and M. bovis Bacille… CONTINUE READING