The Immunology of Allograft Rejection: A Survey of Current Knowledge and a Discussion of Peptide-Specific Anti-Rejection Strategies


The goal of transplantation immunology is to develop strategies for antigen-specific inhibition of transplant rejection. The immune response triggered in the host by the MHC-incompatible organ transplant can lead to the loss of organ function. The MHC peptides created by antigen processing of the donoror allo-MHC molecules of the transplant are a major… (More)


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