The Immune Battle against Helicobacter pylori Infection: NO Offense.

@article{Gobert2016TheIB,
  title={The Immune Battle against Helicobacter pylori Infection: NO Offense.},
  author={Alain P Gobert and Keith T Wilson},
  journal={Trends in microbiology},
  year={2016},
  volume={24 5},
  pages={366-376}
}
Helicobacter pylori is a successful pathogen of the human stomach. Despite a vigorous immune response by the gastric mucosa, the bacterium survives in its ecological niche, thus favoring diseases ranging from chronic gastritis to adenocarcinoma. The current literature demonstrates that high-output of nitric oxide (NO) production by the inducible enzyme NO synthase-2 (NOS2) plays major functions in host defense against bacterial infections. However, pathogens have elaborated several strategies… CONTINUE READING
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