The Ile585Val TRPV1 variant is involved in risk of painful knee osteoarthritis

Abstract

OBJECTIVE To assess if a coding variant in the gene encoding transient receptor potential cation channel, subfamily V, member 1 (TRPV1) is associated with genetic risk of painful knee osteoarthritis (OA). METHODS The Ile585Val TRPV1 variant encoded by rs8065080 was genotyped in 3270 cases of symptomatic knee OA, 1098 cases of asymptomatic knee OA and 3852… (More)
DOI: 10.1136/ard.2010.148122

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