The IgG1/G2 subclass shift – a sensitive, tissue non-specific marker for malignancy. Diagnostic performance with squamous cell carcinoma of the head and neck

@inproceedings{Anderhuber1999TheIS,
  title={The IgG1/G2 subclass shift – a sensitive, tissue non-specific marker for malignancy. Diagnostic performance with squamous cell carcinoma of the head and neck},
  author={W. Anderhuber and W. Steinschifter and E. Schauenstein and A. Gotschuli and Walter Habermann and Michael S Fischer and P. Felsner and Konrad Schauenstein},
  booktitle={British Journal of Cancer},
  year={1999}
}
SummaryA significant decrease in %IgG1 accompanied by an increase in %IgG2 in total serum IgG has been previously reported as a highly sensitive marker for detecting early stages of carcinomas of various localizations. Here we investigated the question as to whether this phenomenon is also observed in sera of patients with squamous cell carcinoma of the head–neck region (SCC-HN), and to evaluate its diagnostic performance in the post-operative monitoring. Using quantitative affinity… CONTINUE READING

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