The Identification of the Sodium Pump

  title={The Identification of the Sodium Pump},
  author={Jens Chr. Skou},
  journal={Bioscience Reports},
  • J. Skou
  • Published 1 August 1998
  • Biology
  • Bioscience Reports
The identification of the sodium potassium pump as a Na+, K+-ATPase is described. 

Na/K-ATPase and Its Role in Signal Transduction

This chapter focuses on the molecular mechanism of Na/K-ATPase-mediated signal transduction and its potential regulatory role in animal physiology and diseases.

Na+/K+-ATPase: A Perspective

Na+/K+-ATPase (NKA), a transmembrane protein, facilitates active transport of three Na+ out of the cell and two K+ into the cell with the expense of an ATP. It plays an important role in regulating

Pumping ions

This is a concise review of the field of ion pumping from the perspective of the authors and concludes with a call for further studies into the role of nanofiltration and its applications in medicine and materials science.

Mechanistic principles of ion transport in the Na,K-ATPase

  • H. Apell
  • Biology, Chemistry
    Russian Journal of Electrochemistry
  • 2017
The Na,K-ATPase is a member of the P-type ATPase family and a primary active ion transporter for Na+ and K+ ions in the cytoplasmic membrane of virtually all animal cells. Considerable progress in

Sodium-potassium-adenosinetriphosphatase-dependent sodium transport in the kidney: hormonal control.

How molecular events at the transporter level account for the physiological changes in tubular handling of sodium promoted by hormones is analyzed to analyze the integrated network of signaling pathways underlying hormone action.

Na+/K+-pump and neurotransmitter membrane receptors

The role of the Na+/K+-pump in neurons is considered, with an emphasis on its role in modulating neurotransmitter receptor, in most, if not all, invertebrate nervous systems.

Distinct Role of the N-terminal Tail of the Na,K-ATPase Catalytic Subunit as a Signal Transducer*

A well conserved Na,K-ATPase motif is identified that binds to the inositol 1,4,5-trisphosphate receptor and can trigger an anti-apoptotic calcium signal.

Na/K Pump and Intracellular Monovalent Cations: Novel Mechanism of Excitation–Transcription Coupling Involved in Inhibition of Apoptosis

This review focuses on the analysis of recent data showing that inhibition of the Na/K pump triggers a signaling cascade independently of modulation of the intracellular [Na+]i/[K+] i ratio.