The ITIM-bearing CLECSF6 (DCIR) is down-modulated in neutrophils by neutrophil activating agents.

@article{Richard2003TheIC,
  title={The ITIM-bearing CLECSF6 (DCIR) is down-modulated in neutrophils by neutrophil activating agents.},
  author={Manon Richard and Nathalie Thibault and Patricia Veilleux and Rock Breton and Andr{\'e} D. Beaulieu},
  journal={Biochemical and biophysical research communications},
  year={2003},
  volume={310 3},
  pages={767-73}
}
The recently discovered CLECSF6 protein displays the features of a receptor involved in the down-modulation of leukocyte activation. Although CLECSF6 has been the focus of the interest of many researchers lately, a Western blot characterization of the protein is still lacking. This highly reduces our ability to gain full knowledge of the biological relevance of this protein in cell responses. We produced two rabbit polyclonal antisera that detected a glycosylated protein at approximately 35kDa… CONTINUE READING

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