The ISWI Chromatin Remodeler Organizes the hsrω ncRNA–Containing Omega Speckle Nuclear Compartments

@inproceedings{Onorati2011TheIC,
  title={The ISWI Chromatin Remodeler Organizes the hsrω ncRNA–Containing Omega Speckle Nuclear Compartments},
  author={Maria Cristina Onorati and Sandra Lazzaro and Moushami Mallik and Antonia Maria Rita Ingrassia and Anna Paola Carreca and Anand Kamal Singh and Deo Prakash Chaturvedi and Subhash C Lakhotia and Davide F. V. Corona},
  booktitle={PLoS genetics},
  year={2011}
}
The complexity in composition and function of the eukaryotic nucleus is achieved through its organization in specialized nuclear compartments. The Drosophila chromatin remodeling ATPase ISWI plays evolutionarily conserved roles in chromatin organization. Interestingly, ISWI genetically interacts with the hsrω gene, encoding multiple non-coding RNAs (ncRNA) essential, among other functions, for the assembly and organization of the omega speckles. The nucleoplasmic omega speckles play important… CONTINUE READING