The IRT1 protein from Arabidopsis thaliana is a metal transporter with a broad substrate range

@article{Korshunova1999TheIP,
  title={The IRT1 protein from Arabidopsis thaliana is a metal transporter with a broad substrate range},
  author={Yulia O. Korshunova and David Eide and W. Gregg Clark and Mary Lou Guerinot and Himadri B. Pakrasi},
  journal={Plant Molecular Biology},
  year={1999},
  volume={40},
  pages={37-44}
}
The molecular basis for the transport of manganese across membranes in plant cells is poorly understood. We have found that IRT1, an Arabidopsis thaliana metal ion transporter, can complement a mutant Saccharomyces cerevisiae strain defective in high-affinity manganese uptake (smf1Δ). The IRT1 protein has previously been identified as an iron transporter. The current studies demonstrated that IRT1, when expressed in yeast, can transport manganese as well. This manganese uptake activity was… CONTINUE READING
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