The IL-17F sequence variant is associated with susceptibility to tuberculosis.

  title={The IL-17F sequence variant is associated with susceptibility to tuberculosis.},
  author={Rong Peng and Jun Qin Yue and Min Han and Yanlin Zhao and Lirong Liu and Li Liang},
  volume={515 1},
The interleukin (IL)-17 gene plays a key role in host defence against infections from microbes, including Mycobacterium tuberculosis. Genetic factors contribute to host defence. However, whether genetic variation in IL-17 is associated with altered susceptibility to tuberculosis is unknown. A total of 596 pulmonary tuberculosis (PTB) patients, 176 extra-pulmonary tuberculosis (EPTB) patients, and 622 control patients from a Chinese Han population were recruited. Two single-nucleotide… CONTINUE READING
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