The IFITM Proteins Mediate Cellular Resistance to Influenza A H1N1 Virus, West Nile Virus, and Dengue Virus

Abstract

Influenza viruses exploit host cell machinery to replicate, resulting in epidemics of respiratory illness. In turn, the host expresses antiviral restriction factors to defend against infection. To find host cell modifiers of influenza A H1N1 viral infection, we used a functional genomic screen and identified over 120 influenza A virus-dependency factors… (More)
DOI: 10.1016/j.cell.2009.12.017

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Cite this paper

@article{Brass2009TheIP, title={The IFITM Proteins Mediate Cellular Resistance to Influenza A H1N1 Virus, West Nile Virus, and Dengue Virus}, author={Abraham L. Brass and I-Chueh Huang and Yair Benita and Sinu P. John and M. Nikhil Krishnan and Eric M. Feeley and Bethany J. Ryan and Jessica L. Weyer and Louise van der Weyden and Erol Fikrig and David J. Adams and Ramnik J. Xavier and Michael Farzan and Stephen J Elledge}, journal={Cell}, year={2009}, volume={139}, pages={1243-1254} }