The Hypocretin/Orexin System: Implications for Drug Reward and Relapse


Hypocretins (also known as orexins) are hypothalamic neuropeptides involved in the regulation of sleep/wake states and feeding behavior. Recent studies have also demonstrated an important role for the hypocretin/orexin system in the addictive properties of drugs of abuse, consistent with the reciprocal innervations between hypocretin neurons and brain areas… (More)
DOI: 10.1007/s12035-012-8255-z


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