The Hypercycle

@article{Eigen2004TheH,
  title={The Hypercycle},
  author={Manfred Eigen and Peter Schuster},
  journal={Naturwissenschaften},
  year={2004},
  volume={65},
  pages={7-41}
}
Topologic methods are used to characterize a particular class of self-replicative reaction networks: the hypercycles. The results show that the properties of hypercycles are sufficient for a stable integration of the information contained in several self-replicative units. Among the catalytic networks studied, hypercyclic organization proves to be a necessary prerequisite for maintaining the stability of information and for promoting its further evolution. The techniques used in this paper… Expand
Hypercycle
TLDR
The most important properties of hypercycles are autocatalytic growth competition between cycles, once-for-ever selective behaviour, utilization of small selective advantage, rapid evolvability, increased information capacity, and selection against parasitic branches. Expand
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Spatio-temporal dynamics in simple asymmetric hypercycles under weak parasitic coupling
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The instability of the autogen
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  • Biology, Medicine
  • Journal of Molecular Evolution
  • 2006
TLDR
The autogen is considered in terms of hypercycle theory, and its dynamic behavior is subjected to fixed point analysis, showing that the components of the autogen are incapable of stable coexistence. Expand
Full analysis of small hypercycles with short-circuits in prebiotic evolution
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Autocatalytic Sets and Biological Specificity
TLDR
This paper studies how the behaviour of a simple binary polymer model can be extended to models where the pattern of catalysis more precisely reflects the ligation and cleavage reactions involved, and establishes a number of new results concerning the structure of RAFs. Expand
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TLDR
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Catalytic reaction sets, decay, and the preservation of information
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  • Chemistry, Physics
  • IEMC '03 Proceedings. Managing Technologically Driven Organizations: The Human Side of Innovation and Change (IEEE Cat. No.03CH37502)
  • 2003
TLDR
A genetic algorithm is used to evolve reaction sets to generate specific polymer distributions under the influence of decay and the beginnings of hypercycle-type structures can be observed, believed to have been an important step toward the evolution of the first living cells. Expand
Reproduction of a protocell by replication of a minority molecule in a catalytic reaction network.
TLDR
It is observed that the protocell divides after a minority molecule is replicated at a slow synthesis rate, and thus, a synchrony between the reproduction of a cell and molecule replication is achieved and the robustness of such protocells against the invasion of parasitic molecules is demonstrated. Expand
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