The Human Genome

  title={The Human Genome},
  author={Elizabeth Pennisi},
  pages={1177 - 1180}
  • E. Pennisi
  • Published 16 February 2001
  • Biology
  • Science
Today's publication of the draft human genome sequence compiled by J. Craig Venter and colleagues represents just the beginning, not the end, of the effort to decipher the human genome. Both the sequence published in this issue and the one in this week's issue of Nature , compiled by lead author Eric Lander of the public genome consortium, have yet to be finished, with all the i's dotted and the t's crossed. But even in this unpolished state, these two books provide the most comprehensive look… 
The Human Genome Project: the next decade
Attention has now shifted towards annotating the genome by assigning function to all the genes, and characterising human genetic variation manifested as single nucleotide polymorphisms (SNPs) to allow the genetic basis of common disorders with “complex” inheritance to be elucidated.
Primer on medical genomics part I: History of genetics and sequencing of the human genome.
The history of genetics is provided, spanning from humankind's initial attempts to understand and influence heredity, to the early scientific work in the field of genetics, and subsequently to the advancements in modern genetics.
The Human Genome Project: Where Are We Now and Where Are We Going?
The HGP continues to exert a significant influence upon the authors' comprehension of human genetics, their understanding of complex disease susceptibility, and ultimately, the manner in which scientific research is currently conducted.
Bioinformatics computation of metabolic models from sequenced genomes
In the early days of the human genome project (HGP), during the late 1980s and early 1990s, there was skepticism that the genome project would produce biologically meaningful information. The reality
The Human genome
This chapter looks in detail at a few sample genes, like the pro-insulin INS gene, in order to prepare for clinical problems such as the treatment of diabetes by genetic engineering.
The digital code of DNA
The discovery of the structure of DNA transformed biology profoundly, catalysing the sequencing of the human genome and engendering a new view of biology as an information science. Two features of
Fruits of human genome project and private venture, and their impact on life science.
A small knowledge base was created by organizing the Human Genome Project (HGP) and its related issues in "Science" magazines between 1996 and 2000. This base revealed the stunning achievement of HGP
Functional proteomics to exploit genome sequences.
The various stages in the progression of knowledge are described, from the genome to the "functional" proteome, with emphasis on a global approach to the protein-protein interactions used to describe the cellular "interactome".
A Metaphor Made in Public
The preliminary results of human genome research have become widely known as “drafts of the human genome.” Drawing on the interaction theory of metaphor, this article shows that take-up of the notion
The human genome project: opportunities, challenges and consequences for population screening.
  • J. Christodoulou
  • Biology
    The Southeast Asian journal of tropical medicine and public health
  • 2003
It is argued that in embracing the new knowledge afforded by the Human Genome Project, the authors must maintain a cautious approach to help minimise the potential risks in order to reap the potentially enormous benefits to society.