The HtrA1 promoter polymorphism, smoking, and age-related macular degeneration in multiple case-control samples.

@article{Tuo2008TheHP,
  title={The HtrA1 promoter polymorphism, smoking, and age-related macular degeneration in multiple case-control samples.},
  author={Jingsheng Tuo and Robert John Ross and George F. Reed and Qing Yu Yan and Jie Jin Wang and Christine M. Bojanowski and Emily Y. Chew and Xiao Ning Feng and Timothy W. Olsen and Frederick L. Ferris and Patricia Mitchell and Carmel Chan},
  journal={Ophthalmology},
  year={2008},
  volume={115 11},
  pages={
          1891-8
        }
}
OBJECTIVE To assess the association and combined effect on the risk of age-related macular degeneration (AMD) by the HtrA1 and complement factor H (CFH) polymorphisms, smoking, and serum cholesterol. DESIGN Clinic-based and population-based case control study. PARTICIPANTS A total of 805 AMD cases and 921 controls from The Eye Clinic of National Eye Institute, Age-Related Eye Diseases Study, Blue Mountain Eye Study Cohort, and Minnesota Lions Eye Bank. METHODS DNA samples were genotyped… CONTINUE READING
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