The Hox proteins Ubx and AbdA collaborate with the transcription pausing factor M1BP to regulate gene transcription.


In metazoans, the pausing of RNA polymerase II at the promoter (paused Pol II) has emerged as a widespread and conserved mechanism in the regulation of gene transcription. While critical in recruiting Pol II to the promoter, the role transcription factors play in transitioning paused Pol II into productive Pol II is, however, little known. By studying how… (More)
DOI: 10.15252/embj.201695751