The History of Steroidal Contraceptive Development: The Estrogens

  title={The History of Steroidal Contraceptive Development: The Estrogens},
  author={J. Goldzieher},
  journal={Perspectives in Biology and Medicine},
  pages={363 - 368}
  • J. Goldzieher
  • Published 1993
  • Medicine
  • Perspectives in Biology and Medicine
  • Our understanding of estrogenic activity began in 1912, when Adler and Fellner in Vienna and Iscovesco in Paris obtained the first ovarian extracts and Haberlandt concluded that ovarian interstitial tissue inhibits ovulation during pregnancy, through the 1920s when Fellner produced sterility in rabbits and mice and Allen and Doisy isolated crystalline estrone. By 1930, Reiprich correctly assigned the antifertility action of the estrogens to pituitary inhibition. The testing of estrogenic… CONTINUE READING
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