The Histone Methyltransferase SUV39H1 Suppresses Embryonal Rhabdomyosarcoma Formation in Zebrafish

@inproceedings{Albacker2013TheHM,
  title={The Histone Methyltransferase SUV39H1 Suppresses Embryonal Rhabdomyosarcoma Formation in Zebrafish},
  author={Colleen E. Albacker and Narie Yoo Storer and Erin M. Langdon and Anthony Dibiase and Yi Zhou and David M Langenau and Leonard I. Zon},
  booktitle={PloS one},
  year={2013}
}
Epigenetics, or the reversible and heritable marks of gene regulation not including DNA sequence, encompasses chromatin modifications on both the DNA and histones and is as important as the DNA sequence itself. Chromatin-modifying factors are playing an increasingly important role in tumorigenesis, particularly among pediatric rhabdomyosarcomas (RMS… CONTINUE READING