The Histone Chaperones FACT and Spt6 Restrict H2A.Z from Intragenic Locations.


H2A.Z is a highly conserved histone variant involved in several key nuclear processes. It is incorporated into promoters by SWR-C-related chromatin remodeling complexes, but whether it is also actively excluded from non-promoter regions is not clear. Here we provide genomic and biochemical evidence that the RNA polymerase II (RNA Pol II) elongation… (More)
DOI: 10.1016/j.molcel.2015.03.030


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