The Herpes Simplex Virus Neurovirulence Factor γ34.5: Revealing Virus–Host Interactions

Abstract

Herpes simplex virus (HSV) is a ubiquitous human pathogen that causes a wide spectrum of disease, ranging from asymptomatic viral shedding to lethal encephalitis and disseminated disease [1,2]. These viruses belong to the neurotropic subfamily of α-herpesviruses, and after initial replication in epithelial cells, HSV enters sensory neurons to establish… (More)
DOI: 10.1371/journal.ppat.1005449

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