The Hemorrhagic Coli Pilus (HCP) of Escherichia coli O157:H7 Is an Inducer of Proinflammatory Cytokine Secretion in Intestinal Epithelial Cells

@inproceedings{Ledesma2010TheHC,
  title={The Hemorrhagic Coli Pilus (HCP) of Escherichia coli O157:H7 Is an Inducer of Proinflammatory Cytokine Secretion in Intestinal Epithelial Cells},
  author={Mar{\'i}a Augusta Escobar Ledesma and Sara A. Ochoa and Ariadnna Cruz and L M Rocha-Ram{\'i}rez and Jaime Mas-Oliva and Carlos A Eslava and Jorge A Gir{\'o}n and Juan Xicoht{\'e}ncatl-Cortes},
  booktitle={PloS one},
  year={2010}
}
BACKGROUND Enterohemorrhagic Escherichia coli (EHEC) O157:H7, the causative agent of hemorrhagic colitis and the hemolytic uremic syndrome (HUS), produces long bundles of type IV pili (TFP) called hemorrhagic coli pili (HCP). HCP are capable of mediating several phenomena associated with pathogenicity: i) adherence to human and bovine epithelial cells; ii) invasion of epithelial cells; iii) hemagglutination of rabbit erythrocytes; iv) biofilm formation; v) twitching motility; and vi) specific… CONTINUE READING

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