The Helicobacter pylori neutrophil-activating protein is an iron-binding protein with dodecameric structure.

@article{Tonello1999TheHP,
  title={The Helicobacter pylori neutrophil-activating protein is an iron-binding protein with dodecameric structure.},
  author={Fiorella Tonello and William G Dundon and Barbara Satin and Maurizio Molinari and Giuseppe Tognon and Guido Grandi and Giuseppe Del Giudice and Rino Rappuoli and Cesare Montecucco},
  journal={Molecular microbiology},
  year={1999},
  volume={34 2},
  pages={238-46}
}
The neutrophil-activating protein (HP-NAP) of Helicobacter pylori is a major 17 kDa antigen of the immune response of infected individuals. Amino acid sequence comparison indicated a high similarity between HP-NAP and both bacterial DNA-protecting proteins (Dps) and ferritins. The structure prediction and spectroscopic analysis presented here indicate a close similarity between HP-NAP and Dps. Electron microscopy revealed that HP-NAP forms hexagonal rings of 9-10 nm diameter with a hollow… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 55 extracted citations

Similar Papers

Loading similar papers…