The Helicobacter pylori homologue of the ferric uptake regulator is involved in acid resistance.

@article{Bijlsma2002TheHP,
  title={The Helicobacter pylori homologue of the ferric uptake regulator is involved in acid resistance.},
  author={Jetta J. E. Bijlsma and Barbara Waidner and Arnoud H. M. van Vliet and Nicky Hughes and Stephanie H{\"a}g and Stefan Bereswill and David J. A. Kelly and Christina M. J. E. Vandenbroucke-Grauls and Manfred Kist and Johannes G Kusters},
  journal={Infection and immunity},
  year={2002},
  volume={70 2},
  pages={606-11}
}
The only known niche of the human pathogen Helicobacter pylori is the gastric mucosa, where large fluctuations of pH occur, indicating that the bacterial response and resistance to acid are important for successful colonization. One of the few regulatory proteins in the H. pylori genome is a homologue of the ferric uptake regulator (Fur). In most bacteria, the main function of Fur is the regulation of iron homeostasis. However, in Salmonella enterica serovar Typhimurium, Fur also plays an… CONTINUE READING

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Iron metabolism in pathogenic bacteria.

Annual review of microbiology • 2000
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