The Hedgehog pathway: potential biomarker and therapeutic applications in urologic malignancies.

Abstract

The Hedgehog pathway has been implicated in the development of several non-urologic malignancies. Recent work suggests that the activation of the glioma-associated GLi family of zinc finger transcription factors may play a role in some urologic malignancies. This review surveys the potential role of the Hedgehog pathway as a new class of biomarker in some urologic cancers.

DOI: 10.1016/j.urolonc.2014.01.021

Cite this paper

@article{Loughlin2014TheHP, title={The Hedgehog pathway: potential biomarker and therapeutic applications in urologic malignancies.}, author={Kevin Raymond Loughlin}, journal={Urologic oncology}, year={2014}, volume={32 5}, pages={546-8} }