The Hamilton Rating Scale for Depression.

@article{Sharp2015TheHR,
  title={The Hamilton Rating Scale for Depression.},
  author={Rachel C. Sharp},
  journal={Occupational medicine},
  year={2015},
  volume={65 4},
  pages={340}
}
The Hamilton Rating Scale for Depression (often abbreviated to HRSD, HDRS or Ham-D) was written in the late 1950s by Max Hamilton, a psychiatrist at Leeds University and originally designed to evaluate the performance of the first group of antidepressants [1]. The scale is still widely used to measure the effectiveness of antidepressant medication in clinical trials. For more than 40 years, it was considered to be the ‘gold standard’ but in the 1990s, its use began to be questioned [2]. 
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