The Hair Follicle: A Specialised UV Receptor in the Human Skin?

@article{Iyengar1998TheHF,
  title={The Hair Follicle: A Specialised UV Receptor in the Human Skin?},
  author={Bhanu Iyengar},
  journal={Neurosignals},
  year={1998},
  volume={7},
  pages={188 - 194}
}
  • B. Iyengar
  • Published 1 June 1998
  • Biology
  • Neurosignals
Coat colour changes in polar animals are related to seasonal variation in photic inputs. The present work was performed to study the photoresponses of hair follicular melanocytes in human skin. The melanocytes, being photosensitive cells, can function as UV biosensors, since dendrites extend towards the source of UV light. Fifty-one skin biopsies from the margin of vitiligo were subjected to whole skin organ cultures. These were exposed to a pulse of UV light to study hair bulb melanocytes in… 

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References

SHOWING 1-10 OF 14 REFERENCES
Melanocytes--a UV-sensitive neural network and circadian rhythms.
TLDR
This sensitivity of the marginal melanocytes, to changes in the duration of UV exposure, simulates the coat color changes in weasels and the polar fox exposed to extreme variations in the day/night cycles.
Neural differentiation as an expression of UV sensitivity of melanocytes.
TLDR
The melanocytes are resistant to UV destruction during the G2 phase as seen on Adriamycin treatment and show a prominent increase in dendricity as well as biphasic activity to produce increased melanin and noradrenaline.
Corticotropin expression by human melanocytes in the skin.
  • B. Iyengar
  • Biology, Medicine
    Pigment cell research
  • 1995
TLDR
It is evident that the melanocyte network varies the MSH/ACTH levels in correlation with repigmentation and depigmentation in the marginal zone in vitiligo by expressing POMC locally and is related to the UV-sensitivity of the melanocytes.
FIBER‐OPTIC PLANT TISSUES: SPECTRAL DEPENDENCE IN DARK‐GROWN AND GREEN TISSUES *
TLDR
Transmission spectra of light guided through several monocot and dicot etiolated tissues show a decreasing red/far red ratio with increasing tissue length, which may have implications for physiological responses mediated by phytochrome.
Hair Color, Molt, and Testis Size in Male, Short-Tailed Weasels Treated with Melatonin
TLDR
It is suggested that the pineal gland product, melatonin, initiates changes in the central nervous system and endocrines which result in molting, growth of the white winter pelage, and reproductive quiescence in the weasel.
An attempt to stimulate cell division in Saccharomyces cerevisiae with weak ultraviolet light.
TLDR
Liquid cultures of the yeast Saccharomyces cerevisiae were irradiated with weak light and no evidence was obtained for stimulation of either yeast growth or division by the incident light, suggesting that very low intensity uv light can stimulate cell division in living organisms.
Effect of adriamycin on the cell cycle traverse and kinetics of cultured human lymphoblasts.
TLDR
Effect of ADM on cell cycle traverse, cell growth, and incorporation of labeled precursors into DNA is dependent on drug concentration and length of exposure to ADM.
Histopathology of Skin, ed 6
  • Philadelphia, Lippincott,
  • 1993
UV guided dendritic growth patterns and the neural networking of melanocytes
  • Experientia
  • 1994
...
...