The Haber-Weiss reaction and mechanisms of toxicity.

@article{Kehrer2000TheHR,
  title={The Haber-Weiss reaction and mechanisms of toxicity.},
  author={James P. Kehrer},
  journal={Toxicology},
  year={2000},
  volume={149 1},
  pages={
          43-50
        }
}
  • J. Kehrer
  • Published 2000
  • Chemistry, Medicine
  • Toxicology
The concept that the highly reactive hydroxyl radical (HO) could be generated from an interaction between superoxide (O(2)(-)) and hydrogen peroxide (H(2)O(2)) was proposed (with Joseph Weiss) in Professor Haber's final paper published in 1934. Until it was recognized that free radicals are produced in biological systems, this finding seemed to have no relevance to biology. However, following the discovery that O(2)(-) was a normal cellular metabolite, it was quickly recognized that the Haber… Expand
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