The HSS3/4 enhancer of Crlz1-IgJ locus is another target of EBF in the pre-B cell stage of B cell development.

@article{Kim2006TheHE,
  title={The HSS3/4 enhancer of Crlz1-IgJ locus is another target of EBF in the pre-B cell stage of B cell development.},
  author={Ja-Yeon Kim and Sung-Kyun Park and Hong-Gi Kim and Sun-Jung Cho and Jiyoung Kim and C. Kang},
  journal={Immunology letters},
  year={2006},
  volume={107 1},
  pages={
          63-70
        }
}
The HSS3/4 enhancer of Crlz1-IgJ locus was first characterized with regard to the activity of HSS1 IgJ promoter in the plasma cells, where both of HSS3/4 enhancer and HSS1 IgJ promoter were found to be opened simultaneously to drive the IgJ gene expression. Unexpectedly, the HSS3/4 enhancer was also found to be opened in the pre-B cells. However, this opening of HSS3/4 enhancer in the pre-B cells could not be related to the IgJ gene expression, because neither the IgJ promoter was opened nor… Expand
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