The HPLC resolution of N-2,4-dinitrophenylated amino acids and peptides stereoisomers on naphthylethylcarbamate-beta-cyclodextrin bonded phase using the acetonitrile-based mobile phase: evidence for the chiral recognition pattern.

Abstract

A facile method of enantioresolving a variety of alpha-amino acids and peptides on naphthylethylcarbamate-beta-cyclodextrin bonded phases (i.e., SN- and RN-beta-CDs) under the elution of acetonitrile-based mobile phase makes use of 2,4-dinitrofluorobenzene (DNFB) as the tagging reagent, which undergoes nucleophilic substitution by the free amino group in… (More)

Topics

Cite this paper

@article{Chen2004TheHR, title={The HPLC resolution of N-2,4-dinitrophenylated amino acids and peptides stereoisomers on naphthylethylcarbamate-beta-cyclodextrin bonded phase using the acetonitrile-based mobile phase: evidence for the chiral recognition pattern.}, author={Shushi Chen}, journal={Amino acids}, year={2004}, volume={27 3-4}, pages={277-84} }