The HGF receptor/Met tyrosine kinase is a key regulator of dendritic cell migration in skin immunity.


The Met tyrosine kinase has a pivotal role in embryonic development and tissue regeneration, and deregulated Met signaling contributes to tumorigenesis. After binding of its cognate ligand hepatocyte growth factor, Met signaling confers mitogenic, morphogenic, and motogenic activity to various cells. Met expression in the hematopoietic compartment is… (More)
DOI: 10.4049/jimmunol.1200729


6 Figures and Tables