The H19 imprinting control region mediates preimplantation imprinted methylation of nearby sequences in yeast artificial chromosome transgenic mice.

Abstract

In the mouse Igf2/H19 imprinted locus, differential methylation of the imprinting control region (H19 ICR) is established during spermatogenesis and is maintained in offspring throughout development. Previously, however, we observed that the paternal H19 ICR, when analyzed in yeast artificial chromosome transgenic mice (YAC-TgM), was preferentially… (More)
DOI: 10.1128/MCB.01003-12

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@article{Okamura2013TheHI, title={The H19 imprinting control region mediates preimplantation imprinted methylation of nearby sequences in yeast artificial chromosome transgenic mice.}, author={Eiichi Okamura and Hitomi Matsuzaki and R N Scott Sakaguchi and Takuya Takahashi and Akiyoshi Fukamizu and Keiji Tanimoto}, journal={Molecular and cellular biology}, year={2013}, volume={33 4}, pages={858-71} }