The Golgi protein GM130 regulates centrosome morphology and function.

  title={The Golgi protein GM130 regulates centrosome morphology and function.},
  author={Andrew Kodani and Christine S{\"u}tterlin},
  journal={Molecular biology of the cell},
  volume={19 2},
The Golgi apparatus (GA) of mammalian cells is positioned in the vicinity of the centrosome, the major microtubule organizing center of the cell. The significance of this physical proximity for organelle function and cell cycle progression is only beginning to being understood. We have identified a novel function for the GA protein, GM130, in the regulation of centrosome morphology, position and function during interphase. RNA interference-mediated depletion of GM130 from five human cell lines… CONTINUE READING

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