The Golgi as a potential membrane source for autophagy.

  title={The Golgi as a potential membrane source for autophagy.},
  author={Jiefei Geng and Daniel J Klionsky},
  volume={6 7},
In macroautophagy (hereafter autophagy), a morphological hallmark is the formation of double-membrane vesicles called autophagosomes that sequester and deliver cytoplasmic components to the lysosome/vacuole for degradation. This process begins with an initial sequestering compartment, the phagophore, which expands into the mature autophagosome. A tremendous amount of work has been carried out to elucidate the mechanism of how the autophagosome is formed. However, an important missing piece in… CONTINUE READING
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