The Golgi-Associated Protein GRASP Is Required for Unconventional Protein Secretion during Development

@article{Kinseth2007TheGP,
  title={The Golgi-Associated Protein GRASP Is Required for Unconventional Protein Secretion during Development},
  author={Matthew A. Kinseth and Christophe Anjard and Danny Fuller and Gianni Guizzunti and William F. Loomis and Vivek Malhotra},
  journal={Cell},
  year={2007},
  volume={130},
  pages={524-534}
}
During Dictyostelium development, prespore cells secrete acyl-CoA binding protein (AcbA). Upon release, AcbA is processed to generate a peptide called spore differentiation factor-2 (SDF-2), which triggers terminal differentiation of spore cells. We have found that cells lacking Golgi reassembly stacking protein (GRASP), a protein attached peripherally to… CONTINUE READING